Abstract: ob＜x＞jective: In this paper, we want to evaluate the effect of sedative and analgesic, dosage and complication rate of dexmedetomidine combined with ropivacaine in childbirth. Methods: 60 parturient women were selected. The patients were randomly divided into two groups, which contains control group (R 30 cases) with ropivacaine (0.1%) PCEA solution and interventional group (RD 30 cases) with ropivacaine (0.1%) and dexmedetomidine (0.5ug/mL) as PCEA solution. The first dose was 0.125% ropivacaine 10mL in group R and 0.125% ropivacaine +0.5ug/mL dexmedetomidine 10mL in group RD. After 30 minutes, the patients were connected with the patient-controlled electronic analgesia pump through the epidural catheter. The maternal PCEA dose was 5mL/h, the locking time was 15min, and the background dose was 8mL/h. We use the Ramsay Sedation Score, VAS score and Improved Bromage Score to evaluate maternal pain and lower limb motor block. Then we observed the PCEA dosage and times. Finally, we calculated the time of labor, Apgar score, and incidence of complications. Results: Compared to R group, Ramsay Sedation Score was significantly increased in RD group, and the difference was statistically significant (P<0.05). PCEA dosage and times were significantly reduced, and the difference was statistically significant (P<0.05). Meanwhile, the incidence of shiver was significantly lower than that of group R (P<0.05). There was no significant difference in VAS score between the two groups. There was no significant difference between the two groups in terms of Improved Bromage Score, duration of labor, Apgar Score and complications (P > 0.05). Conclusion: Adding dexmedetomidine to ropivacaine and fentanyl can improve the sedative effect of labor analgesia of PCEA, reduce the dosage and reduce the incidence of shiver. There was no significant effect on labor time and newborn.Keywords: epidural, analgesia/method; Dex/drug therapy; Maternal; childbirth