Abstract: Objective To investigate the effect of slow and limited-volume fluid resuscitation on blood gas index and coagulation function in pre-hospital emergency patients with hemorrhagic shock. Methods 112 patients with hemorrhagic shock who received pre-hospital emergency treatment in our hospital from August 2015 to August 2017 were selected. 56 patients in the study group were treated with slow and limited-volume fluid resuscitation and 56 patients in the control group were treated with routine fluid resuscitation. We compared the difference the two groups’ blood gas index and coagulation function when they came into emergency department and 60min, 120min and 180min after treatment. Results The arterial partial pressure of oxygen (PaO2) and base access (BE) in the study group were significantly higher than those in the control group (P < 0.05), the BL in the study group were significantly lower than those in the control group (P < 0.05), the prothrombin time (PT) and activated partial thromboplastin time (APTT) in 60 minutes, 120 minutes and 180 minutes after fluid slow and limited-volume fluid resuscitation in the study group were significantly lower than those in the control group (P < 0.05) ，the PLT in 60, 120 and 180 minutes after slow and limited-volume treatment in the study group was significantly higher than that of the control group (P < 0.05), and the DIC incidence and mortality of the study group were significantly lower than that of the control group after slow and limited-volume treatment (P < 0.05).Conclusion Slow and limited-volume fluid resuscitation can improve blood gas index, coagulation function, and reduce the incidence of Disseminated intravascular coagulation（DIC） and the mortality in patients with hemorrhagic shock