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    温馨, 唐天友, 王妤琪, 徐钰梅, 李亮, 章龙珍. 低剂量率脉冲放射治疗晚期复发肿瘤4例报告及文献复习[J]. 徐州医科大学学报, 2022, 42(1): 72-75. DOI: 10.3969/j.issn.2096-3882.2022.01.015
    引用本文: 温馨, 唐天友, 王妤琪, 徐钰梅, 李亮, 章龙珍. 低剂量率脉冲放射治疗晚期复发肿瘤4例报告及文献复习[J]. 徐州医科大学学报, 2022, 42(1): 72-75. DOI: 10.3969/j.issn.2096-3882.2022.01.015
    shu
    The pulsed low dose rate scheme was used in treatment of 4 cases with relapsed cancer and literature review[J]. Journal of Xuzhou Medical University, 2022, 42(1): 72-75. DOI: 10.3969/j.issn.2096-3882.2022.01.015
    Citation: The pulsed low dose rate scheme was used in treatment of 4 cases with relapsed cancer and literature review[J]. Journal of Xuzhou Medical University, 2022, 42(1): 72-75. DOI: 10.3969/j.issn.2096-3882.2022.01.015
    shu

    低剂量率脉冲放射治疗晚期复发肿瘤4例报告及文献复习

    The pulsed low dose rate scheme was used in treatment of 4 cases with relapsed cancer and literature review

      摘要
    • 摘要: 目的：观察低剂量脉冲放射治疗对治疗后复发转移的晚期癌症患者的近期疗效及不良反应的耐受性；方法：报道4例晚期肿瘤复发患者接受低剂量率脉冲照射后1-4月，根据RECIST1.0标准评估其近期疗效及治疗相关不良反应，并对相关文献进行复习。结果：4例患者均顺利完成全程治疗， 2例患者达PR，1例CR，所有患者治疗副反应轻微，耐受性非常好。结论：低剂量率脉冲放射治疗对晚期复发肿瘤患者的局部再治疗，疗效确切，不良反应轻微。期待多中心大样本临床结果，以便推广应用。

       

      Abstract: Objective: To observe the efficacy and safety of the pulsed low dose rate scheme (PLDR) in the treatment of relapsed cancer. Methods: The clinical record of four patients with replased cancer treated with PLDR scheme were analyzed. Their short-term efficacy according to the RECIST 1.0 standard and the related adverse reactions were evaluated, and the relevant literature was reviewed. Results: All the four patients successfully accepted the whole treatment, 2 patients reached PR and 1 patient reached CR. And mild adverse reactions were tolerated. Conclusion: PLDR scheme in the treatment of relapsed cancer is effective, and the adverse effects are tolerated. Multi-center large sample studies should be implemented in order to promote the scheme.

       

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