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    顾青青, 曹兆兰, 章以法. 连云港地区89例儿童新型冠状病毒感染临床分析[J]. 徐州医科大学学报, 2022, 42(7): 543-546. DOI: 10.3969/j.issn.2096-3882.2022.07.013
    引用本文: 顾青青, 曹兆兰, 章以法. 连云港地区89例儿童新型冠状病毒感染临床分析[J]. 徐州医科大学学报, 2022, 42(7): 543-546. DOI: 10.3969/j.issn.2096-3882.2022.07.013
    GU Qingqing,Cao Zhaolan ,ZHANG Yifa[J]. Journal of Xuzhou Medical University, 2022, 42(7): 543-546. DOI: 10.3969/j.issn.2096-3882.2022.07.013
    Citation: GU Qingqing,Cao Zhaolan ,ZHANG Yifa[J]. Journal of Xuzhou Medical University, 2022, 42(7): 543-546. DOI: 10.3969/j.issn.2096-3882.2022.07.013

    连云港地区89例儿童新型冠状病毒感染临床分析

    GU Qingqing,Cao Zhaolan ,ZHANG Yifa

    • 摘要: 目的分析儿童2019新型冠状病毒(2019-nCoV)感染的临床特征。方法分析2022年3月4日—3月22日在连云港市第四人民医院住院治疗的89例2019-nCoV感染患儿的基线情况及临床资料。结果89例患儿中男41例,女48例,无症状感染40例,轻型44例,普通型5例;年龄6个月~14岁,平均年龄(8.07±2.82)岁;89例患儿均有流行病学史,呈聚集性发病;临床表现以发热(28.09%)、咳嗽(16.85%)、流涕(4.50%)为主;实验室检查结果表明无症状感染、轻型、普通型患儿间白细胞、淋巴细胞、C-反应蛋白、降钙素原、D2聚体水平差异无统计学意义(P>0.05),C-反应蛋白在轻型患儿中升高更明显(P<0.05),新型冠状病毒核酸检测N基因和ORF基因CT值在普通型患儿中升高更明显(P<0.05);胸部CT异常8例,表现为肺部片状、结节状或磨玻璃样影。结论儿童新型冠状病毒感染呈聚集性发病,以无症状感染及轻症为主,近期预后良好。C-反应蛋白、新型冠状病毒核酸检测N基因和ORF基因CT值对早期判断病情发展及预后具有参考价值。

       

      Abstract: ob<x>jective To Analysis clinical characteristics of 89 children with 2019-nCoV infection.Methods Analysis of ba<x>seline and clinical data of 89 cases of novel coronavirus infection in children hospitalized in Lianyungang.Results Nnong the 89 children,there are 40 case with asymptomatic infection, 44 case with the light type and 5 with the common type,with a minimum age of 6 month and a maximum age of 14 years. The average ageof inpatientswas 8.07±2.82 years old .There were 41 males and 48 females. All patients have an epidemiological history including 52 families and 30 classes.Clinical manifestations were mainly fever (28.09%), cough (16.85%) and runny nose (4.50%).Laboratory tests show positive or declining white blood cells and lymphocytes.C-reactive protein, calcitoninogen and D2 aggregates are elevated, and C-reactive protein and CT values are significantly elevated in the light group.There are 8 case showed intrapulmonary lamellar, nodular or ground glass shadow on chest CT scan.Conclusion Children with 2019-nCoV infectiongenerally have a clear epidemiological history.Characterized by aggregated morbidity, mild symptoms, predominantly asymptomatic infections and mild illnesses, and a good prognosis for the immediate future.C-reactive protein, novel coronavirus nucleic acid test N gene and ORF gene CT values can be used as experimental indicators for early determination of disease progression and prognosis.

       

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