Abstract: Objective To explore the clinical effectiveness of Savary-Gilliard esophageal dilatation on esophageal strictures caused by different etiologies.Methods A total of 60 patients with esophageal strictures who were admitted to the Third Affiliated Hospital of Xuzhou Medical University from July 2017 to December 2021 and underwent Savary-Gilliard esophageal dilatation were enrolled and their clinical data were retrospectively analyzed.There were 32 cases of esophagogastric anastomotic stenosis after esophageal cancer surgery, 15 cases of esophageal cancer with stenosis after radiotherapy, and 13 cases of esophageal burn with stenosis. Their dysphagia and postoperative feeding were evaluated. The number of dilation times, the diameter of esophageal strictures before and after operation, and postoperative complications were recorded.Results After esophageal dilatation, dysphagia was relieved to various extent in patients with esophageal strictures caused by different etiologies(P≤0.001), with an obviously effective rate of 95% and a total effective rate of 100%. According to follow-up visits at postoperative two months, the total effective rate became 87.3%. The diameter of esophageal strictures were markedly widened(P<0.001), and no postoperative complication was reported.Conclusions Savary-Gilliard esophageal dilatation has definite clinical effectiveness, and can well relieve esophageal strictures caused by different etiologies.