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    郑泽洲. 可调式分流管治疗特发性正常压力脑积水并发症的疗效分析[J]. 徐州医科大学学报, 2020, 40(8): 579-582.
    引用本文: 郑泽洲. 可调式分流管治疗特发性正常压力脑积水并发症的疗效分析[J]. 徐州医科大学学报, 2020, 40(8): 579-582.
    Effect analysis of adjustable shunt on idiopathic normal pressure hydrocephalus[J]. Journal of Xuzhou Medical University, 2020, 40(8): 579-582.
    Citation: Effect analysis of adjustable shunt on idiopathic normal pressure hydrocephalus[J]. Journal of Xuzhou Medical University, 2020, 40(8): 579-582.

    可调式分流管治疗特发性正常压力脑积水并发症的疗效分析

    Effect analysis of adjustable shunt on idiopathic normal pressure hydrocephalus

    • 摘要: 目的:探讨可调式分流管在特发性正常压力脑积水患者的疗效。方法:对本院2016年1月1日到2019年5月30日中符合诊断标准的40例特发性正常压力脑积水患者行脑室腹腔分流术,其中20位患者使用固定压力的分流管(对照组),另外20位患者使用可调式分流管(实验组),观察并记录两组之间的疗效和并发症的发生情况。结果:实验组的特发性正常压力脑积水患者与对照组的患者相比,关于临床症状方面上:实验组的10m折返行走实验时间及步数、MMSE评分,两者之间的差异均具有统计学意义(P<0.05);脑室大小方面:实验组EI及CA,两者之间的差异均具有统计学意义(P<0.05);在病人的预后评估方面:实验组MRS及GOS,两者之间的差异均具有统计学意义(P<0.05)。MoCA评估两组全面认知情况,结果表明对照组的患者在总分、视觉空间、注意力和执行能力评分较低,差异具有统计学意义(P<0.05)。FAB和SWT评估两组的执行功能,结果表明对照组患者在额叶功能评定量表测试中和斯特鲁色词检验中的评分相对较低,两组之间的差异具有统计学意义(P<0.05)。对照组术后感染1例,分流管阻塞2例,分流不足2例,分流过度1例,并发症发生率为30%。实验组术后感染1例,分流管阻塞1例,分流不足及分流过度均为0例,并发症发生率为10%。结论:可调式分流管行脑室腹腔分流术(VPS)来治疗特发性正常压力脑积水病患具有更明显的治疗效果以及更低的并发症发生率,值得进一步应用和推广。

       

      Abstract: ob<x>jective: To investigate the efficacy of adjustable shunt in patients with idiopathic normal pressure hydrocephalus. Methods: Forty patients with idiopathic normal pressure hydrocephalus who met the diagnostic criteria from January 1, 2016 to May 30, 2019 were treated with ventriculo-peritoneal shunt. Twenty patients used a fixed-pressure shunt as a control group, and another 20 patients used an adjustable shunt as an experimental group. The efficacy and complications between the two groups were observed and recorded.Compared with control group, in terms of clinical symptoms, the time nd step number f 10 m reentrant walking test, and MMSE score f the patients were statistically significant (P<0.05). In terms of ventricular size, experimental group EI nd CA f the patients were statistically significant (P<0.05). In terms of prognosis, experimental group MRS and GOS f the patients were statistically significant (P<0.05). MoCA assessed the overall cognitive status of the two groups. The results showed that the patients in the control group had lower scores in total score, visual space, attention and executive ability, and the difference was statistically significant (P<0.05). FAB and SWT evaluated the executive function of the two groups. The results showed that the control group had a relatively low score in the frontal lobe function rating scale test and the Struer color test. The difference between the two groups was statistically significant (P <0.05).In the control group, 1 case had postoperative infection, 2 cases had shunt obstruction, 2 cases had shunt, and 1 case had excessive shunt. The complication rate was 30%. In the experimental group, 1 case was infected, 1 case was blocked by shunt, 0 cases were shunt and shunt, and the complication rate was 10%.Conclusion: Adjustable shunt tube ventriculo-peritoneal shunt for patients with idiopathic normal pressure hydrocephalus has better therapeutic effect and lower incidence of complications, which is worthy of further application and promotion.

       

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