Abstract: ob＜x＞jectives: To evaluate the effect of intrauterine EGF perfusion on improving pregnancy outcome in patients with mild intrauterine adhesions during frozen thawed embryo transfer. Methods: A total of 48 patients with mid intrauterine adhesions waiting for frozen thawed embryo transfer in our center from March 2018 to September 2019 were recruited. All the patients have received treatment of IVF and frozen whole embryo in fresh cycle. Patients were divided into control group and test group randomly. The patients in control group were infused with normal saline and the patients in test group was infused with EGF. The thickness, type and blood flow of the endometrium, the implantation rate, spontaneous abortion rate, biochemical pregnancy rate and clinical pregnancy rate of the two groups were compared.Result: The thickness of endometrium in test group was higher than that in control group (9.39±1.92mm vs (8.23± 1.2mm, P<0.05 ). More type A endometrium was observed in test group. However, the difference was not statistically significant(P>0.05). No significantly changes were observed in the test group regarding to blood flow of the endometrium after treatment(P>0.05). Interestingly, the implantation rate and clinical pregnancy rate in the test group were higher than those in the control group during the follow-up(P<0.05). While, there was no significant difference in the rate of early abortion, multiple pregnancy and ectopic pregnancy.Conclusion: Intrauterine infusion of EGF can improve endometrial receptivity, clinical pregnancy rate and pregnancy outcome of patients with mild intrauterine adhesions by increasing endometrial thickness.