[1]赵连俊.甲状腺功能与抑郁症患者抑郁程度相关性分析)[J].徐州医科大学学报,2019,39(07):534-536.
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甲状腺功能与抑郁症患者抑郁程度相关性分析)()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
39
期数:
2019年07期
页码:
534-536
栏目:
出版日期:
2019-06-25

文章信息/Info

Title:
Analysis of the correlation between thyroid function and depression degree in patients with depression
作者:
赵连俊
文献标志码:
A
摘要:
08例将患者分为研究组31例合并甲状腺功能减退77例不合并甲状腺功能减退抑郁量表8.45±5.39 vs. 22.79±4.67,P=0.000),同时研究组抑郁严重程度分级显著高于对照组(P=0.009)。研究组血清T3(P=0.017)、T4(P=0.000)、FT3(P=0.005)以及FT4(P=0.000)浓度显著低于对照组,血清TSH浓度明显显著高于对照组(P=0.000)。相关性分析发现,抑郁患者HAMD评分与血清T4(P=0.013)及FT4(P=0.008)浓度显著性负相关,与血清TSH浓度显著性正相关(P=0.009)。结论:抑郁症患者抑郁严重程度与甲状腺功能密切相关,需综合治疗。
Abstract:
Objective: To investigate the correlation between thyroid function and depression degree in patients with depression. Method: 108 cases with depression were continuously collected and were divided into a study group (n=31 cases, combined with hypothyroidism) and a control group (n=77 cases, not combined with hypothyroidism), Hamilton depression rating scale (HAMD) scores, difference in serum thyroid hormone concentration and severity of depression were compared between two groups, and the correlation between HAMD scores and serum thyroid hormone concentration were analyzed. Results: HAMD score in the study group was significantly higher than that of the control group (28.45±5.39 vs. 22.79±4.67, P=0.000). Serum T3 (P=0.017), T4 (P=0.000), FT3 (P=0.005) and FT4 (P=0.000) concentrations in the study group were significantly lower than those in the control group, and serum TSH concentrations were significantly higher than that in the control group (P=0.000). Correlation analysis showed that HAMD score of depressed patients was negatively correlated with serum T4 (P=0.013) and FT4 (P=0.008) concentrations, and positively correlated with serum TSH concentrations (P=0.009). Conclusion: The severity of depression was closely related to thyroid function in patients with depression, which requires comprehensive treatment
更新日期/Last Update: 2019-07-11