[1]阚姝,耿德勤.椎基底动脉扩张延长综合征的临床特征及其危险因素研究[J].徐州医科大学学报,2019,39(08):580-584.
 [J].Journal of Xuzhou Medical University,2019,39(08):580-584.
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椎基底动脉扩张延长综合征的临床特征及其危险因素研究()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
39
期数:
2019年08期
页码:
580-584
栏目:
出版日期:
2019-08-25

文章信息/Info

作者:
阚姝耿德勤
文献标志码:
A
摘要:
目的:探讨椎基底动脉延长扩张综合征(VBD)出现临床症状的危险因素,以对其进行早期干预减少并发症。对象与方法:收集从2010-2018年以来诊断的VBD患者,根据症状的有无分为症状性VBD和非症状性VBD。分析两组患者相关临床、影像学及血液学检查结果的差异。结果:共收集184例患者,其中症状组143例(77.7%),非症状组41例(22.3%)。症状性VBD和非症状性VBD在基底动脉直径、两侧椎动脉直径差、中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、C-反应蛋白(CRP)、高同型半胱氨酸(HCY)、有无高血压、椎动脉优势(VAD)偏移度T2 Flair血管内高信号征中有显著差异(P<0.05)。logistic回归分析显示,有无VAD及对症状性VBD有影响意义。结论:症状性VBD患者更容易合并高血压及高同型半胱氨酸血症,相关炎症指标NLR、PLR及CRP明显高于非症状性患者, VAD及FVH为症状性VBD的危险因素。
Abstract:
Objective: To investigate the risk factors of symptomaticVertebrobasilar dolichoectasia (VBD) for early intervention. Participants and methods: This study retrospectively collected patients with VBD from 2010-2018 and was classified into symptomatic VBD and non-symptomatic. The differences in clinical, imaging, and hematological findings between the two groups were analyzed. Results: A total of 184 patients were enrolled, including 143 (77.7%) in the symptom group and 41 (22.3%) in the non-symptomatic group. There were significant differences between symptomatic VBD and asymptomatic VBD in the diameter of basilar artery, the diameter difference of bilateral vertebral artery, the hypertension , neutrophil to lymphocyte ratio(NLR),platelet to lymphocyte ratio(PLR),C-reactive protein(CRP),homocysteine(HCY), VAD(Vertebral artery dominance), the deviation(P<0.05)FLAIR vascular hyperintensity(P<0.05). Logistic regression analysis showed that the presence of VAD and FVH had significant effect on symptomatic VBD. Conclusion: Patients with symptomatic VBD were more likely to be associated with hypertension and hyperhomocysteinemia, and the related inflammatory markers NLR, PLR and CRP were significantly higher than those of non-symptomatic patients. VAD and FVH were risk factors of symptomatic VBD
更新日期/Last Update: 2019-09-18