Abstract: Objective To compare and analyze the clinical therapeutic effect of transurethral plasmakinetic enucleation of bladder tumor (PKEBT) and transurethral resection of bladder tumor (TURBT) for bladder tumor and the value of accurate pathological staging after operation. Methods A total of 100 patients diagnosed with non-muscle-invasive bladder cancer (NMIBC) before surgery were selected in the Affiliated Hospital of Xuzhou Medical University from September 2016 to December 2017, and were divided into TURBT group and PKEBT group (n=50 each). The difference between the two groups on accurate pathological staging, operation time, the rate of muscle-invasive bladder cancer (MIBC) and recurrence rate within 12 months after surgery were compared. Results There was no statistically significant difference in operative time between the two groups (P>0.05). The MIBC detection rate of PKEBT group was higher than TURBT group (24% vs. 8%, P<0.05). The recurrence rate of the PKEBT group was lower than TURBT group at 3, 6, 9 and 12 months postoperatively (2.63%vs. 17.39%, 5.26% vs. 21.73%, 10.52% vs. 28.26%, 13.15% vs. 32.60%, respectively), with statistical significance (P<0.05). Conclusions In the treatment of bladder tumor, PKEBT can completely remove the tumor, and can get more accurate pathological staging and reduce postoperative recurrence rate.