经尿道等离子剜除术治疗膀胱肿瘤的临床研究-《徐州医科大学学报》

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Title:: (81672845) *E-mail:sunheyao@126.com Clinical study of plasmakinetic enucleation for bladder tumor

摘要:: 目的探究经尿道等离子剜除术对于膀胱肿瘤的临床治疗效果，并分析其对精确肿瘤分期的影响。方法选取我院2016年9月至2017年12月术前初步诊断为非肌层浸润性膀胱肿瘤的患者（NMIBC），选取其中分别采用经尿道膀胱肿瘤电切术（TURBT）和经尿道膀胱肿瘤等离子剜除术（PKEBT）治疗的患者各50例，比较两组患者精确病理分期的差异，分析两组患者的手术时长、肌层浸润性膀胱癌（MIBC）检出率和术后12个月内的复发率，探讨两种术式的优缺点。结果两组患者的手术时间比较的差异无统计学意义（P>0.05）。PKEBT组的MIBC检出率高于TURBT组（24%vs8%，P=0.029）。术后3个月，6个月，9个月和12个月的复发率，PKEBT组皆低于TURBT组（2.63%vs17.39%，5.26%vs21.73%，10.52%vs28.26%，13.15%vs32.60%），两者比较具有统计学意义（p<0.05）。结论经尿道等离子剜除术治疗膀胱肿瘤安全有效，可以获得更精确的病理分期。

Abstract:: Objective To investigate the clinical effect of transurethral plasma enucleation on bladder tumor and analyze its effect on accurate tumor staging. Methods A total of 100 Patients diagnosed with non-muscle-invasive bladder cancer(NMIBC) before surgery were selected from September 2016 to December 2017 , and were divided into transurethral resection of bladder tumor (TURBT) group and plasmakinetic enucleation of bladder tumors (PKEBT) group . We compared the difference between the two groups on accurate pathological staging, operation time, the rate of muscle-invasive bladder cancer (MIBC) and recurrence rate within 12 months after surgery. Results There was no statistically significant difference in operative time between the two groups (P>0.05). The MIBC detection rate of PKEBT group is higher than TURBT group (24%vs8%, P=0.029). The recurrence rates of the PKEBT group were lower than TURBT group at 3, 6, 9 and 12 months postoperatively (2.63%vs17.39%, 5.26%vs21.73%, 10.52%vs28.26%, 13.15%vs32.60%, respectively), with statistical significance (p<0.05). Conclusion Plasmakinetic enucleation of bladder tumors is safe and effective in the treatment of bladder neoplasms.