Abstract: Objective We investigate the effect of STN-DBS on primary Parkinson’s disease. The improvement of static tremor was emphatically analyzed. Methods 43 patients with primary Parkinson’s disease treated with bilateral STN-DBS were followed up for an average of 24.5 months. Details are as follows: ①The improvement of UPDRS exercise score H-Y stage and static tremor after DBS operation was calculated. ②The effects of specific static tremor were analyzed from three dimensions including dopamine-responsive and drug-non-responsive left limb onset and right limb onset and upper limb mandibular/lip tremor. ③The program-controlled parameters of tremor were counted to study the correlation between program-controlled parameters and the improvement of static tremor in Parkinson’s disease. Results Postoperative follow-up showed that h-y stage decreased by 0.70 0.58 stage, UPDRS exercise score improved by 47.83% and tremor improved by 70.19%. The left onset type was 60.78% and the right onset type was 76.35%. Upper extremity 85.97% lower extremity 70.77% lower extremity 53.23% lower extremity 70.77% lower extremity 53.23% postoperative program control requires high frequency stimulation tremor of more than 130Hz to get a good improvement. Conclusion STN-DBS had a significant effect on the treatment of motor symptoms of primary Parkinson’s disease, the UPDRS exercise score and tremor were significantly improved, the h-y stage was decreased, but the specific improvement rate of static tremor was improved. The dopamine-free type was better than the reactive type in the patients with right limb onset than the reactive type in the patients with left limb onset in the upper limb and the lower limb and the head. The program control of tremor is still dominated by high frequency stimulation, followed by high voltage.