Abstract:
ob<x>jective To investigate the relationship between the high sensitive C-reactive (hs-CRP) protein level and hemoglobin (Hb) level in non-dialysis chronic kidney disease (CKD) patients. Methods 80 non-dialysis CKD patients were divided into hs-CRP elevation group and hs-CRP normal group according to the hs-CRP level, we researched the changes of renal function indexes, Hb and hs-CRP, investigated the correlation between hs-CRP and Hb. Results There were no statistically significant differences in sex, age, serum creatinine(Scr), b lood urea nitrogen(BUN), cystine C, estimated glomerular filtration(eGFR) and CKD stage between hs-CRP elevation group and hs-CRP group(P>0.05); the level of Hb in hs-CRP elevation group were lower than that in hs-CRP normal group, the level of hs-CRP in hs-CRP elevation group were higher than that in hs-CRP normal group, there were statistically significant differences between them(P < 0.05) ; there was a negative correlation between hs-CRP and Hb in hs-CRP elevation group (r = -0.415), the difference was statistically significant(P < 0.05). Conclusion The degree of anemia is closely related to the state of microinflammation in non-dialysis CKD patients