Abstract: ob＜x＞jective To investigate the correlation between neutrophil / albumin ratio and the severity of sepsis and the predictive value of death risk. Methods from January 2017 to October 2019, 325 children with sepsis were collected from the Anhui Huaibei maternal and child health care hospital. According to the survival conditions 28 days after the onset of sepsis, they were divided into two groups: the survival group 296 cases and the death group 29 cases. According to the PCIs, the survival group was divided into three groups: critical recombination (36 cases), critical recombination (217 cases) and noncritical recombination (43 cases). The differences of neutrophil, albumin and NAR among different groups were compared. The ROC curve was used to analyze the predictive value of NAR on the risk of death in children with sepsis. Results the number of neutrophils, albumin and NAR in sepsis were higher than those in critical and noncritical patients, and the above indexes in death group were higher than those in survival group. ROC curve showed that when NAR level was 0.45, the area under the curve was 0.93, 95% CI was 0.86-0.99, the sensitivity and specificity were 90.91% and 91.67%, respectively, and the maximum Jordan index was 0.83. The difference of NAR between the survival group and the death group was statistically significant (P < 0.001). Conclusion the level of NAR can ob＜x＞jectively reflect the severity of sepsis, and has a positive role in predicting the risk of death in sepsis