Abstract:
ob<x>jective To compare the two-dimensional images, color flow imaging and Young’s modulus of normal cervix, cervical benign lesions and cervical cancer by transvaginal two-dimensional ultrasound, color Doppler flow spectrum and shear wave elastography ((SWE)), and to explore their clinical value in the diagnosis of cervical lesions. Methods 40 cases of normal cervix were included in the normal cervix group, and 30 cases of cervical polyps, cervical myomas and cervical intraepithelial neoplasia confirmed by operation and pathology were included in the benign tumor group. 32 patients with cervical cancer confirmed by operation and pathology were included in the cervical malignant tumor group. The three groups of subjects were examined by transvaginal ultrasound, and their two-dimensional images, color flow imaging, Doppler spectrum and Young’s modulus were measured, and the differences of Young’s modulus and frequency spectrum of the cervix of the three groups were compared. Results in the normal cervix group, the echo was uniform, and there was no or little punctate blood flow (RI > 0.55). In the benign cervical group, the echo was uniform or uneven, with a little punctate blood flow (RI > 0.55). In the cervical malignant group, the echo was uneven, the blood flow was abundant, and the blood flow signal was mostly low resistance (RI < 0.55). Compared with the average value of Young’s modulus of (ROI) in the region of interest of the three groups, the mean Young’s modulus of cervical malignant group (123.28±23.98kPa) was significantly higher than that of cervical benign group (56.12±15.34kPa) and normal group (38.78±9.98kPa)(P < 0.05).There was no significant difference between cervical benign group and normal group (P > 0.05). Conclusion Transvaginal combined with two-dimensional ultrasound, color Doppler flow spectrum and SWE multimodal examination can distinguish benign and malignant cervical lesions and have high clinical value in the diagnosis of cervical cancer.