Abstract: ob＜x＞jective To investigate the duration of rescue and its influencing factors with sudden death before the emergency department of a first-class tertiary hospital. And it can provide some reference for improving quality of death and carrying out intervention research. Methods This study conducted retrospective analysis to collect data of pre-hospital death patients in a first-class tertiary hospital, from January 2015 to December 2019, and the duration of salvage was divided into different grades. Using rank sum test and multiple ordered logistic regression to explore the correlation between gender, age, death reasons, the pre-hospital loss of consciousness’s duration and the duration of salvage. Results The average rescue time of 456 sudden death was 66.61min, and the median was 55.00 (0, 485) min. Among them, 441 patients (96.71%) received basic life support, and 425 patients (93.20%) established advanced airway. Univariate analysis revealed that the statistically differences of rescue time and different genders, ages and causes of sudden death were significant (all P < 0.05). Multiple logistic regression analysis consequences revealed that male, age 60 or below, and non-sudden were the risk factors of rescue time (all P < 0.05). Conclusion The duration of rescue for sudden death patients pre-hospital is generally longer and the quality of death in this group is low. And hope that rescue work in the future can pay more attention to the patient’s life quality at the end of life, to carry out a reasonable and effective rescue recovery.