[1]王功硕,夏婷婷,史家欣*.间充质干细胞在急性呼吸窘迫综合征及2019冠状病毒病中的应用展望[J].徐州医科大学学报,2022,42(03):231-234.[doi:10.3969/j.issn.2096-3882.2022.03.014]
　Application prospect of mesenchymal stem cells in acute respiratory distress syndrome and coronavirus disease 19[J].Journal of Xuzhou Medical University,2022,42(03):231-234.[doi:10.3969/j.issn.2096-3882.2022.03.014]
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间充质干细胞在急性呼吸窘迫综合征及2019冠状病毒病中的应用展望()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
42
期数:
2022年03期
页码:
231-234
栏目:
出版日期:
2022-03-25

文章信息/Info

Title:
Application prospect of mesenchymal stem cells in acute respiratory distress syndrome and coronavirus disease 19
作者:
王功硕; 夏婷婷; 史家欣*
徐州医科大学附属连云港医院呼吸与危重症医学科，江苏连云港222006
关键词:
间充质干细胞; 急性呼吸窘迫综合征; 细胞外囊泡; 2019冠状病毒病
分类号:
R563.8
DOI:
10.3969/j.issn.2096-3882.2022.03.014
文献标志码:
A
摘要:
急性呼吸窘迫综合征（ARDS）是临床常见危重症，各种感染如严重急性呼吸综合征（SARS）、2019冠状病毒病（COVID-19）均可表现为ARDS，其死亡率高，缺乏有效治疗手段。间充质干细胞（MSC）作为一种新型的治疗方法，在临床前及临床研究中表现出较强的抗炎和组织修复能力，其安全性也得到了部分证实，是治疗ARDS的潜在有效措施之一。
Abstract:
Acute respiratory distress syndrome (ARDS) is a common and critical clinical disease. Various infections such as severe acute respiratory syndrome (SARS), coronavirus disease 19 (COVID-19) can cause ARDS. ARDS has a high mortality rate and lacks effective treatment methods. Mesenchymal stem cells(MSC), as a new treatment method, shows strong anti-inflammatory and tissue repair ability in preclinical and clinical studies, and its safety has also been partially confirmed, which is one of the potential effective measures to treat ARDS. This review will review the application of MSC in ARDS and COVID-19.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金（81300052）；江苏省六大人才高峰项目（2019-SWYY-324）；江苏省青年医学重点人才项目（QNRC2016504）；连云港市卫健委项目（202016）；南京医科大学康达学院项目（KD2020KYJJYB022）*通信作者,E-mail：shijiaxin909@126.com
更新日期/Last Update: 2022-05-09