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    王忠诚, 张玉东, 胡献礼, 刘超侠. 徐州地区癫痫发病情况与抗癫痫药物使用情况回顾性队列分析[J]. 徐州医科大学学报, 2022, 42(3): 175-180. DOI: 10.3969/j.issn.2096-3882.2022.03.004
    引用本文: 王忠诚, 张玉东, 胡献礼, 刘超侠. 徐州地区癫痫发病情况与抗癫痫药物使用情况回顾性队列分析[J]. 徐州医科大学学报, 2022, 42(3): 175-180. DOI: 10.3969/j.issn.2096-3882.2022.03.004
    Trends in etiologic features and utilization of antiepileptic drugs in Xuzhou: a retrospective cohort study[J]. Journal of Xuzhou Medical University, 2022, 42(3): 175-180. DOI: 10.3969/j.issn.2096-3882.2022.03.004
    Citation: Trends in etiologic features and utilization of antiepileptic drugs in Xuzhou: a retrospective cohort study[J]. Journal of Xuzhou Medical University, 2022, 42(3): 175-180. DOI: 10.3969/j.issn.2096-3882.2022.03.004

    徐州地区癫痫发病情况与抗癫痫药物使用情况回顾性队列分析

    Trends in etiologic features and utilization of antiepileptic drugs in Xuzhou: a retrospective cohort study

    • 摘要: 目的评估徐州市癫痫发病特点及抗癫痫药物的使用特点。方法选取2017年12月—2019年12月于徐州市中心医院就诊的癫痫患者。通过问卷调查和病历复核采集临床资料。结果本研究共募集199例患者,脑血管疾病是成人组(29.9%)和老年组(80.0%)患者最常见的癫痫病因,脑外伤(75.0%)是儿童继发性癫痫的主要原因。超过46.7%的患者使用一种抗癫痫药物进行治疗;无论使用单一抗癫痫药物治疗还是多种抗癫痫药物联合使用,丙戊酸都是最常使用的抗癫痫药物(单药治疗76.2%,联合使用91.8%)。结论徐州地区癫痫患者的病因随年龄的不同而有所差异,脑血管疾病是成年和老年患者最常见的病因。丙戊酸是徐州地区最常使用的抗癫痫药物。

       

      Abstract: ob<x>jective: To assess the evolution of etiologic features and antiepileptic drug (AED) treatment patterns in Intensive Care Unit from 2017 to 201 9.Methods: A retrospective cohort study was performed by collecting the medical records of patients newly diagnosed with epilepsy in Xuzhou Central Hospital from December 201 7 to December 201 9. Patients were followed until the end of data availability. Results: Among 1 99 patients, cerebrovascular disorder was the most common cause in groups of adults (28.6%) and elderly individuals (78.1%). Cerebral trauma (20%) was the major cause of symptomatic epilepsy among children. More than 46.6% of participants were using AED monotherapy. Valproic acid (VPA) was the AED most frequently utilized as monotherapy (76.9%) and within multitherapy (91.7%). Conclusions: Our data showed that the etiologic features varied with the age of patients with epilepsy. Cerebrovascular disorders are the most common cause of epilepsy among adults and elderly individuals . VPA is widely used for the treatment of epilepsy in Xuzhou

       

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