[1]刘玉平.HFNC在重症肺炎合并呼吸衰患儿中的临床应用[J].徐州医科大学学报,2020,40(07):513-516.
 high flow nasal cannula in neonates with severe pneumonia and respiratory failure[J].Journal of Xuzhou Medical University,2020,40(07):513-516.
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HFNC在重症肺炎合并呼吸衰患儿中的临床应用()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
40
期数:
2020年07期
页码:
513-516
栏目:
出版日期:
2020-07-30

文章信息/Info

Title:
high flow nasal cannula in neonates with severe pneumonia and respiratory failure
作者:
刘玉平
文献标志码:
A
摘要:
目的 经鼻导管高流量氧疗(HFNC)治疗的。方法 2017年月1日至201年月日期间在采用数字表法随机分为两组,每组例。观察组给予HFNC,对照组给予~L/min,观察两组患h、h、24h、、PaO2、PaCO2、O2的变化情况,同时对比两组患儿痰液粘稠度、气管插管机械通气率入住时间的差别。结果 观察组、、PaO2、PaCO2、O2分别为(138.75±5.18)次/min、(44.46±3.06)次/min、(95.67±8.61)mmHg、(45.33±4.61)mmHg、(93.08±3.96)%,对照组mmHg、(50.13±3.92)mmHg、(91.13±8.01)%,2组比较差异具有统计学意义( t=3.197、5.510、-2.314、3.406、-2.005,P<0.05);(t=4.406,P<0.05) (Z=3.25,P<0.05)。结论 HFNC
Abstract:
【 Abstract 】 Objective To evaluate the clinical effects of transnasal high flow oxygen therapy (HFNC) in neonates with severe pneumonia and respiratory failure. Methods 54 neonates with severe pneumonia and respiratory failure in our hospital from Mar 1, 2017 to Feb 28, 2018 were randomly divided into observation group(27 cases) and control group(27 cases) with digital table method. The observation group were received with HFNC, and the control group with oxygen humidification device with ordinary Bubble Type for double nasal congestion 0.5-2 L/min. The heart rate, respiratory rate, PaO2, PaCO2 and SpO2 changes were evaluated before treatment, treatment for 1 h, 12 h and 24 h in both groups, at the same time, sputum viscosity, tracheal intubation mechanical ventilation rate, continuous positive airway pressure (CPAP), NICU stay time were compared in the course of treatment of difference. Results Through two different methods of treatment, the heart rate, respiratory rate, PaO2, PaCO2, SpO2were(138.75±5.18) times/ min,(44.46±3.06) times/ min,(95..67±8.61) mmHg,(45.33±4.61) mmHg,(93.08±3.96) % in the observation group, respectively, compared with (148.04±7.62) times/ min,(52.44±5.76) times/ min,(80.48±13.70) mmHg,(50.13±3.92) mmHg and(91.13±8.01) % in the control group, which had significant differences( t= 3.197, 5.510, -2.314, 3.406, -2.005, P < 0.05); The NICU stay time in observation group was( 175.2±46.15) h, respectively, which was much shorter than that in the contorl group(261.61±69.28) h, the difference was statistically significant (t=4.406,P<0.05); Comparison of sputum viscosity between observation group and control group, which had significant differences( Z=3.25, P<0.05). Conclusions HFNC is a new and effective way of oxygen therapy that can effectively treat neonates with severe pneumonia and respiratory failure, which can effectively relieve symptoms, improve lung oxygenation, reduce complications and improve prognosis.
更新日期/Last Update: 2020-07-29