高级检索
    林奇泗, 李开金, 高剑, 杜康彭. 深裂竹根七乙酸乙酯提取物中的化学成分及抗肿瘤活性研究[J]. 徐州医科大学学报, 2019, 39(12): 868-871.
    引用本文: 林奇泗, 李开金, 高剑, 杜康彭. 深裂竹根七乙酸乙酯提取物中的化学成分及抗肿瘤活性研究[J]. 徐州医科大学学报, 2019, 39(12): 868-871.
    antitumor effects and chemical components of the ethyl acetate extracts from Disporposis pernyi[J]. Journal of Xuzhou Medical University, 2019, 39(12): 868-871.
    Citation: antitumor effects and chemical components of the ethyl acetate extracts from Disporposis pernyi[J]. Journal of Xuzhou Medical University, 2019, 39(12): 868-871.

    深裂竹根七乙酸乙酯提取物中的化学成分及抗肿瘤活性研究

    antitumor effects and chemical components of the ethyl acetate extracts from Disporposis pernyi

    • 摘要: 目的 研究深裂竹根七中酸乙酯提取物中化合物的种类与活性。方法 采用系统剂法和柱色谱法提取分离深裂竹根七乙酯乙酯。使用MTT结果 从深裂竹根七乙酸乙酯提取物中分离并鉴别了三种成分,分别为其中白桦脂醇为首次从深裂竹根七中分离到。提取物对结论 深裂竹根七乙酸乙酯提取物对。

       

      Abstract: Objective To investigate the chemical constituents and pharmacological activity of the ethyl acetate extract from Disporposis pernyi. Methods The compounds in the ethyl acetate extract of Disporposis pernyi were extracted and separated by systematic solvent extraction and column chromatography. The molecular structures were identified by nuclear magnetic resonance(NMR), mass spectrometry(MS) and thin layer chromatography (TLC). The inhibitory activity of extracts against human breast cancer cell line MCF-7 was determined by MTT method. Results Three components were isolated and identified, which were Betulin, β-Daucosterol and Luteolin. Betulin was first isolated from the Disporposis pernyi. The extract has inhibitory effect on the proliferation of MCF-7. Conclusions The inhibitory activity of ethyl acetate extract of Disporposis pernyi on human breast cancer cell MCF-7, in which components such as Betulin play a certain role

       

    /

    返回文章
    返回