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    卞宏. 阻塞性睡眠呼吸暂停低通气综合征发生日间高碳酸血症的相关因素分析[J]. 徐州医科大学学报, 2019, 39(12): 902-905.
    引用本文: 卞宏. 阻塞性睡眠呼吸暂停低通气综合征发生日间高碳酸血症的相关因素分析[J]. 徐州医科大学学报, 2019, 39(12): 902-905.
    Analysis of related factors of daytime hypercapnia in obstructive sleep apnea hypopnea syndrome[J]. Journal of Xuzhou Medical University, 2019, 39(12): 902-905.
    Citation: Analysis of related factors of daytime hypercapnia in obstructive sleep apnea hypopnea syndrome[J]. Journal of Xuzhou Medical University, 2019, 39(12): 902-905.

    阻塞性睡眠呼吸暂停低通气综合征发生日间高碳酸血症的相关因素分析

    Analysis of related factors of daytime hypercapnia in obstructive sleep apnea hypopnea syndrome

    • 摘要: 目的:探讨和分析阻塞性睡眠呼吸暂停低通气综合征患者发生日间高碳酸血症的相关因素。 方法:选取2018年10月至2019年5月徐州医科大学附属医院收治的阻塞性睡眠呼吸暂停低通气综合征患者22例为高碳酸血症OSAHS组,46例为非高碳酸血症OSAHS组。比较2组的一般资料、动脉血气分析和多导睡眠图相关指标,并对PaCO2与相关指标进行相关性分析。 结果: 高碳酸血症OSAHS组患者的体重指数(body mass index,BMI)、颈围、胸围、腰围、臀围和爱泼沃斯思睡量表(Epworth sleepness scale ,ESS)评分、平均血氧饱和度(mean O2 Saturation ,MSaO2)、PaCO2、HCO3-均明显高于非高碳酸血症OSAHS组(p<0.05),高碳酸血症OSAHS组PaO2低于的非高碳酸血症OSAHS组,且差异具有统计学意义(p<0.05)。PaCO2与BMI、颈围、胸围、腰围、臀围、ESS评分、HCO3-和平均血氧饱和度(MSaO2)呈明显正相关(p<0.05),PaCO2与PaO2呈明显负相关(p<0.05)。 结论:阻塞性睡眠呼吸暂停低通气综合征患者发生日间高碳酸血症与BMI、中心性肥胖、MSaO2有关,因此当OSAHS患者BMI、ESS评分升高、MSaO2降低时,应注意对阻塞性睡眠呼吸暂停低通气综合征患者进行动脉血气分析检测,明确有无日间高碳酸血症。

       

      Abstract: Objective To explore and analyze the factors associated with daytime hypercapnia in patients with obstructive sleep apnea hypopnea syndrome. Methods 22 patients with obstructive sleep apnea hypopnea syndrome admitted to the Hospital of Xuzhou Medical University from October 2018 to May 2019 were treated with hypercapnia OSAHS and 46 patients with non-hypercapnia OSAHS. The general data of 2 groups, arterial blood gas analysis and polysomnography related indicators were compared, and the correlation analysis between PaCO 2 and related indicators was carried out. Results Body mass index (BMI), neck circumference, chest circumference, waist circumference, hip circumference, and Epworth sleepness scale (ESS) score, mean O 2 saturation(MSaO 2) in patients with hypercapnia OSAHS, PaCO2, HCO3- were significantly higher than non-hypercapnia OSAHS group (p<0.05), hypercapnia OSAHS group had lower PaO 2 than non-hypercapnia OSAHS group, and the difference was Statistical significance (p < 0.05). PaCO 2 was positively correlated with BMI, neck circumference, chest circumference, waist circumference, hip circumference, ESS score, HCO 3- and mean oxygen saturation (MSaO2) (p<0.05), and PaCO2 was significantly negatively correlated with PaO 2 (p<0.05). Conclusion Daytime hypercapnia in patients with obstructive sleep apnea hypopnea syndrome is associated with BMI, central obesity, and MSaO2, so obstructive sleep apnea should be noted when OSAHS patients have elevated BMI, ESS scores, and decreased MSaO2. Patients with OSAHS should be tested for arterial blood gas analysis to determine whether they have daytime hypercapnia.

       

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