Abstract:
Objective To explore and analyze the factors associated with daytime hypercapnia in patients with obstructive sleep apnea hypopnea syndrome. Methods 22 patients with obstructive sleep apnea hypopnea syndrome admitted to the Hospital of Xuzhou Medical University from October 2018 to May 2019 were treated with hypercapnia OSAHS and 46 patients with non-hypercapnia OSAHS. The general data of 2 groups, arterial blood gas analysis and polysomnography related indicators were compared, and the correlation analysis between PaCO 2 and related indicators was carried out. Results Body mass index (BMI), neck circumference, chest circumference, waist circumference, hip circumference, and Epworth sleepness scale (ESS) score, mean O 2 saturation(MSaO 2) in patients with hypercapnia OSAHS, PaCO2, HCO3- were significantly higher than non-hypercapnia OSAHS group (p<0.05), hypercapnia OSAHS group had lower PaO 2 than non-hypercapnia OSAHS group, and the difference was Statistical significance (p < 0.05). PaCO 2 was positively correlated with BMI, neck circumference, chest circumference, waist circumference, hip circumference, ESS score, HCO 3- and mean oxygen saturation (MSaO2) (p<0.05), and PaCO2 was significantly negatively correlated with PaO 2 (p<0.05). Conclusion Daytime hypercapnia in patients with obstructive sleep apnea hypopnea syndrome is associated with BMI, central obesity, and MSaO2, so obstructive sleep apnea should be noted when OSAHS patients have elevated BMI, ESS scores, and decreased MSaO2. Patients with OSAHS should be tested for arterial blood gas analysis to determine whether they have daytime hypercapnia.