Abstract: ob＜x＞jective:To investigate the prognostic factors of patients with hydrocephalus after traumatic brain injury.Methods：Retrospective analysis of clinical data of 200 patients with hydrocephalus after traumatic brain injury treated in the affilliated hospital of xuzhou medical university from June 2014 to June 2019. Patients’ gender, age, causes of craniocerebral injury, GCS score at admission, pupillary response, presence or absence of SAH, ventricular hemorrhage, midline shift, increased intracranial pressure, and subdural effusion were collected. Univariate analysis was performed on selected factors, and multivariate logistic regression analysis was performed ba＜x＞sed on the results to explore the influencing factors of prognosis in patients with hydrocephalus after traumatic brain injury.Results：Univariate analysis revealed that there was no significant difference between gender and causes of craniocerebral injury in patients with good prognosis and poor prognosis (P> 0.05).Differences in age, GCS score at admission, pupil response, SAH, intraventricular hemorrhage, midline shift, increased intracranial pressure, and subdural effusion were related to the prognosis of patients with hydrocephalus after head injury (P <0.05). Multivariate analysis found that age, GCS score at admission, and intraventricular hemorrhage were independent risk factors affecting the prognosis of hydrocephalus after brain injury.Conclusions:Age, GCS score on admission and intraventricular hemorrhage were independent risk factors for the prognosis of Hydrocephalus after brain injury. For the elderly, preoperative patients with low GCS score should be highly concerned and make a detailed and reasonable review plan. It is an effective way to improve the prognosis of patients with intraventricular hemorrhage.