[1]江兴松.凝结芽胞杆菌联合美沙拉嗪治疗非特异性回肠末端溃疡疗效观察[J].徐州医科大学学报,2020,40(07):509-512.
 Clinical efficacy of Bacillus coagulans compound joint mesalazine in treatment of nonspecific terminal ileum ulcer[J].Journal of Xuzhou Medical University,2020,40(07):509-512.
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凝结芽胞杆菌联合美沙拉嗪治疗非特异性回肠末端溃疡疗效观察()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
40
期数:
2020年07期
页码:
509-512
栏目:
出版日期:
2020-07-30

文章信息/Info

Title:
Clinical efficacy of Bacillus coagulans compound joint mesalazine in treatment of nonspecific terminal ileum ulcer
作者:
江兴松
文献标志码:
A
摘要:
目的:观察凝结芽胞杆菌联合美沙拉嗪治疗非特异性回肠末端溃疡临床疗效。方法: 选取收治的回肠末端非特异性溃疡患者121例。随机分为两组:观察组62例,对照组59例。观察组应用凝结芽孢杆菌活菌片联合美沙拉嗪片治疗,对照组应用凝结芽孢杆菌活菌片治疗,4周为1疗程,持续治疗3 个疗程。观察两组的临床疗效、内镜下治疗效果及临床症状总积分改善情况。结果:观察组临床治疗总有效率为95.2%,对照组为81.4%。两组比较差异有统计学意义(χ2=4.36 P<0.05)。观察组内镜下总有效率为93.5%,对照组为77.9%。两组比较差异有统计学意义(χ2=4.85 P<0.05)。治疗后,两组的临床症状总积分均较治疗前下降,差异均有统计学意义(t观=20.20,t对=13.72,P<0.05)。治疗后观察组较对照组总积分下降明显,组间比较差异有统计学意义(t=3.61,P<0.05)。结论:凝结芽胞杆菌联合美沙拉嗪治疗非特异性回肠末端溃疡效果明显,值得临床推广应用。
Abstract:
ob<x>jective:To investigate the efficacy of Bacillus coagulans joint mesalazine in treatment of nonspecific terminal ileum ulcer. Method:Selected 121 cases of nonspecific terminal ileum ulcer patients,they were randomly dividede into the observation group (n=62) and the control group (n=59), the observation group was used Bacillus coagulans joint mesalazine treatment,the control group was used Bacillus coagulans treatment,all patients received 1 course of treatment for 4 weeks and 3courses of continuous treatment. The clinical therapeutic effect, the endoscopic therapeutic effect and the improvement of the total score of clinical symptoms of the two groups were observed. Result:The total effective rate of clinical treatment in observation group was 95.2%,and that in control group was 81.4%,the total efficiency of the observation group was significantly higher than that of control group (χ2=4.36, P<0.05) .The total effective rate of endoscopic treatment was 93.5% in the observation group and 77.9% in the control group,and the difference was tatistically significant (χ2=4.85, P<0.05) . After treatment,the total score of clinical symptoms of the two groups was lower than that before treatment, the difference was statistically significant (observation group:t=20.20,control group:t=13.72,P<0.05) ,The total score of clinical symptoms of observation group was significantly lower than that of the control group, there was statistically significant difference between the two groups(t=3.61,P<0.05).Conclusion:Bacillus coagulans joint mesalazine in treatment of nonspecific terminal ileum ulcer has obvious effect,its worthy of clinical application.
更新日期/Last Update: 2020-07-29