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    林望望, 黄伟. 腹部脂肪分布特征在克罗恩病诊断中的应用[J]. 徐州医科大学学报, 2022, 42(2): 138-142. DOI: 10.3969/j.issn.2096-3882.2022.02.013
    引用本文: 林望望, 黄伟. 腹部脂肪分布特征在克罗恩病诊断中的应用[J]. 徐州医科大学学报, 2022, 42(2): 138-142. DOI: 10.3969/j.issn.2096-3882.2022.02.013
    Application of abdominal fat distribution characteristics in the diagnosis of Crohn’’’’s disease[J]. Journal of Xuzhou Medical University, 2022, 42(2): 138-142. DOI: 10.3969/j.issn.2096-3882.2022.02.013
    Citation: Application of abdominal fat distribution characteristics in the diagnosis of Crohn’’’’s disease[J]. Journal of Xuzhou Medical University, 2022, 42(2): 138-142. DOI: 10.3969/j.issn.2096-3882.2022.02.013

    腹部脂肪分布特征在克罗恩病诊断中的应用

    Application of abdominal fat distribution characteristics in the diagnosis of Crohn’’’’s disease

    • 摘要: 目的:探讨CT定量分析腹部脂肪分布特征在克罗恩病(CD)诊断中的价值。方法:回顾性分析2017年1月-2019年6月于我院行CT小肠造影检查的43例CD患者和27例正常者的资料,分别测量腹部脂肪体积、脂肪平均密度和腰围。比较CD组和正常组脂肪分布特征参数。构建Logistic回归模型并运用ROC曲线评价脂肪分布特征参数在CD诊断中的效能。应用Spearman相关分析,评价脂肪分布特征参数与CRP的相关性。结果:正常组皮下脂肪体积(SFV)、总脂肪体积(TFV)和腰围(WC)高于CD组(P<0.05),正常组皮下脂肪平均密度(MDSF)、内脏脂肪平均密度(MDVF)和脂肪体积指数(FVI)低于CD组(P<0.05)。两组间内脏脂肪体积(VFV)差异无统计学意义(P=0.175)。Logistic回归模型在CD诊断中的敏感性和特异性分别为69.8%和88.9%,曲线下面积为0.848。内脏脂肪平均密度与CRP呈正相关。结论:CT定量分析腹部脂肪分布特征在CD诊断中具有价值。

       

      Abstract: ob<x>jective: The study was to explore the value of CT quantitative analysis of abdominal fat distribution characteristic in the diagnosis of Crohn’s disease.Methods: Retrospective analysis was performed on 43 CD patients and 27 normal patients who underwent CT enterography in our hospital from January 2017 to June 2019. Abdominal fat volume, mean fat density and waist circumference of the subject were measured respectively. Compare the fat distribution characteristic parameters of CD group and normal group. Logistic regression model was constructed and ROC curve was used to assess the efficacy of fat distribution characteristic parameters in CD diagnosis. Spearman correlation analysis was used to assess the correlation between abdominal fat distribution characteristic parameters and C-reactive protein.Results: The subcutaneous fat volume (SFV), total fat volume (TFV) and waist circumference (WC) of normal group were higher than those of CD group(P<0.05). The mean density of subcutaneous fat (MDSF), mean density of visceral fat (MDVF) and fat volume index (FVI) of normal group were lower than those of CD group(P <0.05). There was no significant difference in visceral fat volume (VFV) between the two groups(P=0.175). The sensitivity and specificity of the logistic regression model in the diagnosis of CD were 69.8% and 88.9% respectively, and the area under the curve was 0.848. The mean density of visceral fat (MDVF) was positively correlated with CRP.Conclusions: CT quantitative analysis of abdominal fat distribution characteristic is useful in diagnosis of Crohn’s disease.

       

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