Abstract:
ob<x>jective: The study was to explore the value of CT quantitative analysis of abdominal fat distribution characteristic in the diagnosis of Crohn’s disease.Methods: Retrospective analysis was performed on 43 CD patients and 27 normal patients who underwent CT enterography in our hospital from January 2017 to June 2019. Abdominal fat volume, mean fat density and waist circumference of the subject were measured respectively. Compare the fat distribution characteristic parameters of CD group and normal group. Logistic regression model was constructed and ROC curve was used to assess the efficacy of fat distribution characteristic parameters in CD diagnosis. Spearman correlation analysis was used to assess the correlation between abdominal fat distribution characteristic parameters and C-reactive protein.Results: The subcutaneous fat volume (SFV), total fat volume (TFV) and waist circumference (WC) of normal group were higher than those of CD group(P<0.05). The mean density of subcutaneous fat (MDSF), mean density of visceral fat (MDVF) and fat volume index (FVI) of normal group were lower than those of CD group(P <0.05). There was no significant difference in visceral fat volume (VFV) between the two groups(P=0.175). The sensitivity and specificity of the logistic regression model in the diagnosis of CD were 69.8% and 88.9% respectively, and the area under the curve was 0.848. The mean density of visceral fat (MDVF) was positively correlated with CRP.Conclusions: CT quantitative analysis of abdominal fat distribution characteristic is useful in diagnosis of Crohn’s disease.