[1]孙蕾,盛晓静,殷勤*.南京地区健康儿童血清维生素A、D、E水平分析[J].徐州医科大学学报,2022,42(03):207-211.[doi:10.3969/j.issn.2096-3882.2022.03.010]
　Analysis of serum vitamin A, D and E levels in healthy children[J].Journal of Xuzhou Medical University,2022,42(03):207-211.[doi:10.3969/j.issn.2096-3882.2022.03.010]
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南京地区健康儿童血清维生素A、D、E水平分析()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
42
期数:
2022年03期
页码:
207-211
栏目:
出版日期:
2022-03-25

文章信息/Info

Title:
Analysis of serum vitamin A, D and E levels in healthy children
作者:
孙蕾; 盛晓静; 殷勤*
南京医科大学第二附属医院儿童保健科，江苏南京210011
关键词:
儿童; 维生素A; 维生素D; 维生素E
分类号:
R174
DOI:
10.3969/j.issn.2096-3882.2022.03.010
文献标志码:
A
摘要:
目的：了解南京医科大学第二附属医院健康儿童血清脂溶性维生素A、D、E的水平。方法：收集我院健康儿童体检的资料并分组，每例儿童血清维生素A(VA)、维生素E(VE)水平采用反相高效液相色谱荧光检测法测定，每例儿童血清25羟维生素D（25-OH-VD）水平采用液相串联质谱法测定，分析各年龄组维生素A、D、E的水平。结果：健康体检儿童共2151例，血清VA平均水平为（0.32±0.08）mg/L，以≤1岁组VA水平最低（0.29±0.075）mg/L；所有受检少儿低水平VA检出率为37.09%（798/2151），≤1岁组检出率最高（54.19%）；血清25-OH-VD平均水平（34.24±9.31）ng/mL，＞6岁组25-OH-VD 水平最低（25.58±8.67）ng/mL；所有受检者中低水平25-OH-VD检出率为33.56%（722/2151），＞6岁组检出率最高（77.89%）；血清VE平均水平为（10.69±3.57）mg/L，＞6岁组最低（8.59±1.96）mg/L；所有受检者中低水平VE检出率为5.57%（120/2151），＞6岁组检出率最高（20%）。结论：≤1岁组的维生素A水平最低，维生素D和E水平与年龄有关，年龄越大，维生素D和E水平越低。
Abstract:
ob＜x＞jective To investigate the level of serum soluble vitamin A , D, E in healthy children in the Second Affiliated Hospital of Nanjing Medical University. Methods The data of physical examination of healthy children in our hospital were collected and grouped. The serum vitamin A (VA) and vitamin E (VE) levels of each child were determined by reversed-phase high-performance liquid chromatography fluorescence detection. The serum of each child was 25- hydroxy vitamin D (25-OH-VD) levels were determined by liquid phase tandem mass spectrometry, and the levels of vitamins A, D, and E in each age group were analyzed. Results A total of 2151 healthy children were examined. The average serum VA level was (0.32 ± 0.08) mg / L, and the lowest VA level was ≤1 year old (0.29 ± 0.075) mg / L. The detection rate of low-level VA for all children was 37.09. % (798/2151), the detection rate was highest in the ≤1 year old group (54.19%); the average serum 25-OH-VD level (34.24 ± 9.31) ng / mL, and the lowest 25-OH-VD level in the 6 year old group (25.58 ± 8.67) ng / mL; the detection rate of low-level 25-OH-VD in all subjects was 33.56% (722/2151), and the detection rate was highest in the 6-year-old group (77.89%); the average serum VE level was ( 10.69 ± 3.57) mg / L, the lowest in the 6-year-old group (8.59 ± 1.96) mg / L; the detection rate of low-level VE in all subjects was 5.57% (120/2151), and the highest in the 6-year-old group (20%) . Conclusions Vitamin A levels are the lowest in the ≤1 year old group. Vitamin D and E levels are related to age. The older the age, the lower the vitamin D and E levels.

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更新日期/Last Update: 2022-05-09