[1]孙婷婷,姚进,朱君雅,等.视网膜缺血再灌注损伤机制研究进展[J].徐州医科大学学报,2020,40(11):853-858.[doi:10.3969/j.issn.2096-3882.2020.11.016]
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视网膜缺血再灌注损伤机制研究进展()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
40
期数:
2020年11期
页码:
853-858
栏目:
出版日期:
2020-11-25

文章信息/Info

Title:
Research progress on the mechanism of retinal ischemia reperfusion injury
作者:
孙婷婷姚进朱君雅姚牧笛
南京医科大学附属眼科医院眼底病科,江苏 南京 210029
关键词:
视网膜缺血再灌注损伤 机制 进展 坏死性凋亡 自噬 长链非编码RNA
DOI:
10.3969/j.issn.2096-3882.2020.11.016
文献标志码:
A
摘要:
视网膜缺血再灌注损伤(retinal ischemia reperfusion injury,RIRI)广泛存在于糖尿病视网膜病变、青光眼、视网膜静脉阻塞以及早产儿视网膜病变等缺血性眼病的病理过程,该病变可造成视网膜功能紊乱,严重影响患者的视力恢复,最终会导致视力损害和视力丧失.深入研究并详细阐明RIRI发生、发展的具体机制,对于视网膜缺血性疾病的防治具有重要的科学价值与临床意义.近年来,有关RIRI的研究逐渐成为眼科领域的研究热点并取得了重要进展.本文结合新近关于RIRI的研究进展,对其作用机制和分子调控网络进行简要综述.
Abstract:
In clinic, as a common ischemic eye disease, retinal ischemia-reperfusion injury (RIRI) severely impairs the function of retina, affects the eyesight health of teenagers and has aroused widespread concern in the society. Previous studies have founded several mechanisms which can facilitate RIRI. However, there are still great disputes among scholars on the existing mechanism. Understand and study the different injury mechanisms of RIRI has been of huge importance for the prevention and treatment of retinal ischemic diseases
更新日期/Last Update: 2020-12-15