[1]潘彬(青年),经历,曹梦函.艾塞那肽联合ACDF治疗神经根型颈椎病的疗效分析[J].徐州医科大学学报,2020,40(09):650-654.
 Clinical analysis of the effect of ACDF combined with Exendin-4 on cervical spondylotic radiculopathy[J].Journal of Xuzhou Medical University,2020,40(09):650-654.
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艾塞那肽联合ACDF治疗神经根型颈椎病的疗效分析()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
40
期数:
2020年09期
页码:
650-654
栏目:
出版日期:
2020-09-25

文章信息/Info

Title:
Clinical analysis of the effect of ACDF combined with Exendin-4 on cervical spondylotic radiculopathy
作者:
潘彬(青年)经历曹梦函
文献标志码:
A
摘要:
目的 探究艾塞那肽联合颈椎前路椎间盘减压植骨融合术(ACDF)在治疗神经根型颈椎病的治疗效果。方法 选取2017年2月至2019年12月我院因神经根型颈椎病入院且行ACDF手术治疗的患者,选取其中分别采用单纯ACDF手术治疗(ACDF组)和ACDF手术联合艾塞那肽治疗(ACDF+艾塞那肽组)患者各50例。运用疼痛视觉模拟评分(VAS评分),日本骨科协会评估治疗分数(JOA),颈椎曲度及手术节段活动度评估(ROM)和肌电图检查对2组病人的临床疗效进行比较,运用血糖监测检测患者血糖变化。结果 在治疗1月和3月后, ACDF+艾塞那肽组VAS评分,JOA评分和上肢肌电图检测结果明显优于ACDF组,差异有统计学意义(P<0.05);2组病人颈椎曲度及手术节段ROM和血糖检测无明显差异(P>0.05)。结论 艾塞那肽联合ACDF治疗神经根型颈椎病的效果优于传统的单纯ACDF手术,且对患者血糖没有显著影响。
Abstract:
ob<x>jective To explore the therapeutic effect of Exendin-4 combined with anterior cervical disc decompression and fusion (ACDF) on the treatment of cervical spondylotic radiculopathy. Methods Patients admitted to our hospital for cervical spondylotic radiculopathy and operated on ACDF from February 2017 to December 2019 were selected. Among them, 50 patients were treated with ACDF alone (ACDF group) and 50 patients were treated with ACDF combined with Exendin-4 (ACDF+ Exendin-4 group).Visual analogue scale (VAS) score, Japanese Orthopaedic Association(JOA) score, the changes of cervical curvature and range of motion (ROM)of the operative segments and electromyography examination were used to compare the clinical outcomes of the two groups. Blood glucose was monitored. Results After 1 month and 3 months of treatment, VAS score, JOA score and electromyography of ACDF+ Exendin-4 group were significantly better than those of ACDF group, The difference was statistically significant ( P < 0.05).There was no significant difference in cervical curvature, ROM and blood glucose between the two groups ( P > 0.05). Conclusion The effect of ACDF combined with Exendin-4 in the treatment of cervical spondylotic radiculopathy is superior to the traditional ACDF alone, and has no significant effect on blood glucose.
更新日期/Last Update: 2020-10-12