[1]周健,孙珣,胡小义,等.甲钴胺复合罗哌卡因行肋间神经阻滞对胸腔镜[J].徐州医科大学学报,2021,41(03):189-193.[doi:10.3969/j.issn.2096-3882.2021.03.007]
 Effects of mecobalamin combined with ropivacaine for intercostal nerve block onthe postoperative depression in patients undergoing thoracoscopic surgery[J].Journal of Xuzhou Medical University,2021,41(03):189-193.[doi:10.3969/j.issn.2096-3882.2021.03.007]
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甲钴胺复合罗哌卡因行肋间神经阻滞对胸腔镜()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
41
期数:
2021年03期
页码:
189-193
栏目:
出版日期:
2021-03-25

文章信息/Info

Title:
Effects of mecobalamin combined with ropivacaine for intercostal nerve block onthe postoperative depression in patients undergoing thoracoscopic surgery
作者:
周健1孙珣1 胡小义1李想1刘鹤3曹君利12*
1.徐州医科大学附属医院麻醉科,江苏徐州221002;2.徐州医科大学江苏省麻醉学重点实验室,江苏徐州221002;3.浙江大学医学院附属湖州医院麻醉科,浙江湖州313003
关键词:
胸腔镜手术甲钴胺 肋间神经阻滞术后抑郁
分类号:
R614.2
DOI:
10.3969/j.issn.2096-3882.2021.03.007
文献标志码:
A
摘要:
目的探索甲钴胺复合罗哌卡因行肋间神经阻滞对胸腔镜手术患者术后抑郁情绪的影响。方法选取在徐州医科大学附属医院择期行胸腔镜手术患者110例,采用随机数字表法分成甲钴胺复合罗哌卡因组(试验组)及罗哌卡因组(对照组),每组55例。术毕行肋间神经阻滞。试验组注射甲钴胺(0.5 mg/1ml)1ml+0.5%罗哌卡因10 ml+生理盐水,共20 ml,对照组注射0.5%罗哌卡因10 ml+生理盐水,共20 ml。采用抑郁自评量表(self-rating depression scale,SDS)评价并记录2组患者术后抑郁情绪状态;采用疼痛数字评分法(numerical rating scale,NRS)评价并记录患者的疼痛评分。结果试验组患者中轻微疼痛(NRS评分≤3分)为40例(78.4%),对照组为30例(56.6%),2组差异具有统计学意义(P<0.05);试验组患者术后2个月抑郁情绪(SDS评分>50)发生率是15.7%,对照组是34.0%,2组差异具有统计学意义(P<0.05)。结论甲钴胺复合罗哌卡因行肋间神经阻滞可以通过改善胸腔镜手术患者术后疼痛降低患者术后抑郁情绪的风险。
Abstract:
ObjectiveTo investigate the effects of mecobalamine combined with ropivacaine for intercostal nerve block on the postoperative depression in patients undergoing thoracoscopic surgery.MethodsA total of 110 patients who underwent thoracoscopic surgery in the Affiliated Hospital of Xuzhou Medical University were randomly divided into two groups (n=55): a mecobalamine combined with ropivacaine group (an experiment group) and a ropivacaine group (a control group). After surgery, intercostal nerve block was performed. The experiment group was injected with 1 ml of mecobalamin(0.5 mg/1ml) +10 ml of 0.5% ropivacaine+normal saline (totally 20 ml), while the control group was injected with 10 ml of 0.5% ropivacaine + normal saline (totally 20 ml).The Self-Rating Depression Scale (SDS) was used to evaluate the postoperative depression of the two groups.The Numerical Rating Scale (NRS) was used to evaluate the pain of the patients. ResultsThe number of patients with mild pain (NRS score≤ 3) was 40 (78.4%) for the experimental group and was 30 (56.6%) for the control group, which was statistically different (P< 0.05). Two months after surgery,the incidence of depression was 15.7% for the experimental group and 34.0% for the control group, which was statistically different (P<0.05). ConclusionsMecobalamine combined with ropivacaine for intercostal nerve block can reduce the risk of postoperative depression through improving postoperative pain in patients after thoracoscopic surgery.
更新日期/Last Update: 2021-04-25