[1]万重阳,葛娇,赵婷婷,等.红细胞分布宽度在预测真性红细胞增多症复发中的作用[J].徐州医科大学学报,2022,42(05):343-348.[doi:10.3969/j.issn.2096-3882.2022.05.006]
 The role of red blood cell distribution width in predicting the relapse of polycythemia vera[J].Journal of Xuzhou Medical University,2022,42(05):343-348.[doi:10.3969/j.issn.2096-3882.2022.05.006]
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红细胞分布宽度在预测真性红细胞增多症复发中的作用()
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《徐州医科大学学报》[ISSN:2096-3882/CN:32-1875/R]

卷:
42
期数:
2022年05期
页码:
343-348
栏目:
出版日期:
2022-05-25

文章信息/Info

Title:
The role of red blood cell distribution width in predicting the relapse of polycythemia vera
作者:
万重阳葛娇赵婷婷李振宇*
徐州医科大学附属医院血液科,江苏徐州221002
关键词:
真性红细胞增多症 复发 红细胞分布宽度
分类号:
R555+.1
DOI:
10.3969/j.issn.2096-3882.2022.05.006
文献标志码:
A
摘要:
摘要:目的分析真性红细胞增多症(polycythemia vera,PV)患者的临床指标,探讨红细胞分布宽度(red blood cell distribution width,RDW)对预测PV复发的影响。方法选取2016—2021年于徐州医科大学附属医院初诊的100例PV患者的临床资料并进行分析整理,根据治疗后是否出现血液学复发分为复发组(n=18)与非复发组(n=82),分别比较2组临床资料,以COX单因素分析筛选出PV复发的影响因素,并纳入COX多因素分析。结果PV复发患者,其红细胞计数(red blood cell count,RBC)、RDW均高于非复发组,差异有统计学意义(P<0.05)。COX多因素回归分析显示,RDW是PV复发的独立危险因素。结论复发PV患者初检外周血RDW水平高于非复发患者,外周血RDW对预测PV复发有一定的价值。
Abstract:
ob<x>jective To analyze the clinical indexes of patients with polycythemia vera (PV) and explore the effect of red blood cell distribution width (RDW) on the recurrence of PV. Methods The clinical data of 100 newly diagnosed PV patients in the affiliated hospital of Xuzhou Medical University from 2016 to 2021 were analyzed and sorted out. They were divided into relapsed group and non- relapsed group according to whether they relapsed after treatment. The clinical data of each group were compared, and the influencing factors for PV relapse were screened out by COX single factor test, which was included in COX multivariate analysis. Results The mean values of red blood cell count(RBC) and RDW in relapsed PV patients were higher than those in non- relapsed PV patients , and the difference was statistically significant ( P < 0.05). COX regression analysis showed that RDW was an independent risk factor for PV relapse. Conclusion The level of RDW in relapsed PV patients is higher than that in non-relapse d patients, and RDW has certain value in predicting the re lapse of PV.

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备注/Memo

备注/Memo:
*通信作者,E-mail:lizhenyumd@163.com
更新日期/Last Update: 2022-06-07