Abstract: ob＜x＞jective To investigate the predictive value of neutrophil/lymphocyte ratio (NLR) in new-onset heart failure in elderly patients with acute non-ST-segment elevation myocardial infarction without revascularization therapy. Methods Retrospective collection of senile acute non-ST segment elevation myocardial infarction patients without reascularization patients’ basic information, laboratory test results and related indicators, such as cardiovascular adverse events will be whether the new heart failure is divided into two groups, compared two groups of clinical features, Logistic regression analysis the influence factors of new heart failure occurs, the ROC curve evaluation prediction value. Results The incidence of new heart failure in elderly patients with acute non-ST-segment elevation myocardial infarction without revascularization was 53.66%. Multivariate logistic regression analysis showed that NLR was an independent risk factor for new-onset heart failure in elderly patients with acute non-ST-segment elevation myocardial infarction without revascularization therapy(HR=1.158，95%CI?1.~1.290，P=0.0）. The ROC curve area was 0.7 (95%CI: 0.706-0.855, P<0.01), the sensitivity was 71.2%, and the specificity was 76.2%. Conclusion NLR can be used as a predictor of new heart failure in elderly patients with acute non-ST-segment elevation myocardial infarction without revascularization therapy