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    综合吸气肌训练联合早期弹力阻抗运动对慢性心力衰竭患者心肺功能及预后的影响

    Effects of comprehensive inspiratory muscle training combined with early elastic resistance exercise on cardiopulmonary function and prognosis of patients with chronic heart failure

    • 摘要: 目的 探究综合吸气肌训练联合早期弹力阻抗运动对慢性心力衰竭(CHF)患者心肺功能及预后的影响。方法 前瞻性选取2021年8月—2023年12月中国人民解放军空军军医大学第二附属医院收治的CHF患者104例,使用随机数表法分为联合组(52例)和对照组(52例)。对照组给予早期弹力阻抗运动干预,联合组在对照组基础上联合综合吸气肌训练干预,观察2组干预前后心肺功能左心室射血分数(LVEF)、峰值氧耗量(VO2 peak)、无氧阈氧耗量(VO2 at)及二氧化碳当量斜率(VE/VCO2 slope)、吸气肌功能最大吸气压(MIP)、吸气峰流速(PIF)、呼吸功能和运动耐力Brog呼吸困难评分、6 min步行试验(6MWT)、生活质量明尼苏达心力衰竭生活质量量表(MLHFQ)评分,以及治疗后6个月内不良心血管事件发生情况。结果 干预后,与对照组相比,联合组LVEF、VO2 peak、VO2 at、MIP、PIF水平和6MWT距离更高(P<0.05),联合组VE/VCO2 slope水平更低(P<0.05),Brog评分、MLHFQ评分、不良心血管事件发生率更低(P<0.05)。结论 综合吸气肌训练联合早期弹力阻抗运动干预能够改善CHF患者心肺功能和呼吸功能,增强患者吸气肌强度和运动耐力,提升患者生活质量,降低不良心血管事件发生率,值得临床推广。

       

      Abstract: Objective To investigate the effects of combined inspiratory muscle training and early elastic resistance exercise on pulmonary function and prognosis in patients with chronic heart failure (CHF). Methods A prospective study was conducted on 104 CHF patients who were admitted to the Second Affiliated Hospital of the Air Force Military Medical University from August 2021 to December 2023. The patients were randomly divided into two groups: a combined group (n=52) and a control group (n=52). The control group received early elastic resistance exercise intervention, while the combined group received the same intervention as the control group in addition to combined inspiratory muscle training. Their heart and lung functions left ventricular ejection fraction (LVEF), peak oxygen consumption (VO2 peak), anaerobic threshold oxygen consumption (VO2 at), and the carbon dioxide equivalent slope (VE/VCO2 slope), inspiratory muscle function maximum inspiratory pressure (MIP), and peak inspiratory flow (PIF), respiratory function and exercise endurance Borg Dyspnea Scale, and 6-minute walk test (6MWT), quality of life Minnesota Living with Heart Failure Questionnaire (MLHFQ) score, and adverse cardiovascular events within 6 months post-treatment were recorded. Results After intervention, the combined group showed significant increases in LVEF, VO2 peak, VO2 at, MIP, PIF, and 6MWT distance (P<0.05) compared with the control group. The combined group also presented decreases in VE/VCO2 slope (P<0.05), and decreases in Borg score, MLHFQ score, and incidence of adverse cardiovascular events (P<0.05). Conclusions Combined inspiratory muscle training and early elastic resistance exercise intervention in CHF patients can improve heart and lung functions, respiratory function, inspiratory muscle strength, and exercise endurance. It also enhances quality of life and reduces the incidence of adverse cardiovascular events, making it worthy of clinical promotion.

       

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