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    超声评估补中益气丸治疗产后压力性尿失禁的临床疗效

    Evaluation of clinical effect of Buzhong Yiqi pill on postpartum stress urinary incontinence by ultrasound

    • 摘要: 目的 探讨经超声评估补中益气丸治疗产后压力性尿失禁的临床疗效。方法 选择80例产后压力性尿失禁患者,按照随机数字表法分为观察组(n=40)和对照组(n=40)。对照组给予神经肌肉电刺激与生物反馈治疗。观察组在对照组基础上,给予补中益气丸治疗。于治疗后8周、3个月进行临床疗效评估。于治疗前及治疗后8周、3个月,对比患者的尿失禁次数、盆底肌力评分、尿垫重量。经会阴三维超声评估患者静息、Valsalva状态时盆底裂孔面积、膀胱颈角度、膀胱颈与耻骨联合下缘距离。结果 治疗后8周,2组的总有效率差异无统计学意义(P>0.05);观察组治疗后3个月的总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后8周、3个月,2组尿失禁次数、尿垫重量均低于治疗前,盆底肌力评分均高于治疗前(P<0.05);2组在治疗后8周、3个月的尿失禁次数、盆底肌力评分、尿垫重量差异有统计学意义(P<0.05)。治疗后8周、3个月,2组患者在静息、Valsalva状态时的盆底裂孔面积、膀胱颈角度明显小于治疗前,膀胱颈与耻骨联合下缘距离明显大于治疗前,且2组同时期上述指标比较,差异均有统计学意义(P<0.05)。结论 补中益气丸可提高产后压力性尿失禁的疗效,经会阴三维超声可为骨盆功能评估提供客观指标。

       

      Abstract: Objective To evaluate the clinical effect of Buzhong Yiqi pill in the treatment of postpartum stress urinary incontinence by ultrasound. Methods A total of 80 cases of postpartum stress urinary incontinence were divided into an observation group (n=40) and a control group (n=40) according to the random number table. The control group was treated with neuromuscular electrical stimulation and biofeedback. The observation group was treated with Buzhong Yiqi pill on the basis of the control group. The clinical effect was evaluated 8 weeks and 3 months after treatment. The frequency of urinary incontinence, the score of pelvic floor muscle strength and the weight of urinary pad were compared before treatment, 8 weeks and 3 months after treatment. Three dimensional ultrasound was used to evaluate the area of the pelvic floor cleft, the angle of the bladder neck and the distance between the bladder neck and the pubic symphysis. Results At 8 weeks after treatment, there was no significant difference in the total effective rate between the two groups (P>0.05). The total effective rate of the observation group was higher than that of the control group (P<0.05). At 8 weeks and 3 months after treatment, the frequency of urinary incontinence and the weight of urinary pad in the two groups were lower than that before treatment, and the score of pelvic floor muscle strength was higher than that before treatment (P<0.05). There were significant differences in the frequency of urinary incontinence, the score of pelvic floor muscle strength and the weight of urinary pad between the two groups at 8 weeks and 3 months after treatment (P<0.05). At 8 weeks and 3 months after treatment, the area of the pelvic floor fissure and the angle of the bladder neck in the resting and Valsalva state of the two groups were significantly lower than that before treatment, and the distance between the bladder neck and the lower edge of the pubic symphysis was significantly higher than that before treatment. The difference between the two indexes was statistically significant (P<0.05). Conclusions Buzhong Yiqi pill can improve the effect of postpartum stress urinary incontinence, and three-dimensional ultrasound of perineum can provide objective index for pelvic function.

       

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