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    血栓弹力图在宫颈癌患者术后下肢深静脉血栓的应用

    Thrombelastography coagulation index may be a predictor of Deep venous thrombosis in cervical cancer patients

    • 摘要: 目的 评估血栓弹力图预测宫颈癌患者术后下肢深静脉血栓发生的临床价值。 方法 选取2017年1月至11月期间于徐州医科大学附属医院(以下简称我院)妇科确诊为宫颈癌患者并行腹腔镜下宫颈癌根治术50例患者为研究对象,根据术后是否发生血栓,将其分为血栓组12例和非血栓组38例;研究对象分别于术前、术后进行TEG、常规凝血功能检测、下肢深静脉血管超声检查。通过ROC曲线,比较TEG各参数、常规凝血功能各指标预测宫颈癌患者术后发生下肢深静脉血栓的敏感性及特异性。结果 两组患者术前各指标均无明显差异(P>0.05);与非血栓组术后各指标相比,血栓组K值、CI值和D-二聚体差异具有统计学意义(P<0.05)。通过ROC曲线下面积比较,K值、MA值、CI值和D-二聚体指标ROC曲线下面积大于0.5,其中CI值ROC曲线下面积最大(A>0.7)。结论 以上结果表明,血栓弹力图中的K值、MA值和CI值在宫颈癌患者术后下肢深静脉血栓发生具有一定的预测价值。

       

      Abstract: Objective Deep vein thrombosis(DVT) is a well-recognized complication gynecological oncology patients and has an impact on the overall outcome. The purpose of this study was to identify whether thrombelastography. Methods A total of 50 cases of Surgical treatment of cervical cancer were selected from January 2017 to November in XuZhou Medical University Affiliated Hospital, as the experimental group ,According to whether there is a thrombus, the experimental group was divided into 12 cases of thrombus group and 3 8 cases of non thrombus group .TEG,routine coagulation Function and Deep venous color Doppler ultrasound were performed in preoprative and postoperative.In addition,TEG and routine coagulation parameters were compared by ROC curve to evaluate the sensitivity and specificity of deep vein thrombosis in cervical cancer patients. Results Compared with non thrombus group,the K,CI and D-dimer in thrombus group had significantly different(P<0.05). By comparing the under the ROC curve,the area under the K value 、MA value、CI valueand D-Dimer were more than 0.5,among them,the area under the ROCcurve of CI value was the largest(>0.7). Conclusion These results indicated that the TEG K value、MA value and CI value may be predictive of DVT in cervical cancer patients

       

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