Abstract: To explore the effect of the gushenantai pills combined with progesterone capsule on the treatment of threatened abortion and its effects on the levels of serum statin A,β-HCG and PRL.Method：Selected 110 patients with threatened abortion who had been treated in our hospital from Sep 2015 to Sep 2017, and equally divided them into the control group and the study group. The study group was treated with gushenantai pills combined with progesterone capsule, while the control group was treated with progesterone capsule. To explore therapeutic efficiency and the serum levels of inhibin A, β-HCG，PRL and progesterone.Results: The therapeutic efficiency in the study group was 92.73%, that was higher than that in the control group 72.73%(P<0.05); One, two and three weeks after the treatment, the inhibin A in both groups were significant increased(P<0.05), and the level in the study was higher than that in the control group(P<0.05); What’s more, the levels of β-HCG, PRL and progesterone in both groups were significant increased(P<0.05), and the levels in study group were significant higher than that in the control group(P<0.05). Conclusion: The gushenantai pills combined with progesterone capsule can effect treat the threatened abortion, through increasing the serum inhibin,β-HCG and PRL, which is worth promoted clinically