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    优思明对人工流产术后出血、月经周期及意外妊娠情况的影响

    The influence of Yasmin on hemorrhage, menstrual cycle and accidental pregnancy after induced abortion

    • 摘要: 目的:探讨优思明对人工流产术后阴道出血、月经周期及意外妊娠情况的影响。方法:以2016年5月至2017年9月期间在我院进行人工流产术的366例患者为研究对象,根据患者术后是否口服短效复方避孕药优思明分为观察组和对照组,观察组190例,对照组176例。观察组患者人工流产术后给予优思明进行避孕;对照组患者采用其他方式进行避孕。比较两组患者人工流产术后阴道出血、月经周期、意外妊娠及生殖激素水平变化情况和并发症发生情况。结果:观察组患者人工流产术后的阴道出血时间、出血量和阴道分泌物增多的比例均显著低于对照组患者,差异均有统计学意义(P <0.05)。观察组患者人工流产术后月经复潮时间和月经恢复情况均明显优于对照组,差异有统计学意义(P <0.05)。观察组患者术后3周的子宫内膜厚度显著高于对照组,而闭经、痛经、经前期综合征和术后6个月内再次妊娠的比例均显著低于对照组,以上差异均有统计学意义(P <0.05)。观察组患者人工流产术后雌二醇(E2)上升程度显著高于对照组,而黄体生成素(LH)和孕激素(PRL)下降程度均显著高于对照组,差异均有统计学意义(P <0.05)。术后观察组患者的并发症发生率均显著低于对照组患者,差异有统计学意义(P <0.05)。结论:人工流产术后应用优思明可显著减少阴道出血,帮助子宫内膜修复和月经周期恢复,且避孕效果好,并发症少,值得在临床推广应用。

       

      Abstract: Objective: To investigate the effect of Yasmin on vaginal bleeding, menstrual cycle and accidental pregnancy after abortion. Methods: The 366 patients who underwent abortion in our hospital from May 2016 to September 2017 were the subjects of the study, according to whether oral short-acting compound pill yasmin after operative, patients were divided into observation group and control group, 190 cases in observation group, 176 cases in control group. The patients in the observation group were given birth control after induced abortion. The control group had other methods of contraception. The changes of vaginal bleeding, menstrual cycle, accidental pregnancy and reproductive hormone levels and complications were compared between the two groups. Results: The proportion of vaginal bleeding time, bleeding amount and vaginal secretion after induced abortion in the observation group were significantly lower than that in the control group, and the difference was statistically significant (P <0.05). The period of menstruation after induced abortion in the observation group was significantly better than that in the control group, and the difference was statistically significant (P <0.05). The endometrial thickness of 3 weeks after abortion in observation group were significantly higher than the control group, and the amenorrhea, dysmenorrhea and premenstrual syndrome and again within six months after pregnancy in observation group were significantly lower than the control group, the differences were statistically significant (P < 0.05). The estradiol (E2) degree rise in observation group of patients with abortion was significantly higher than that in control group, and luteinizing hormone (LH) and progesterone drops (PRL) levels were significantly higher than the control group, the differences were statistically significant (P < 0.05).The incidence of complications in observation group was significantly lower than that in the control group, and the difference was statistically significant (P <0.05). Conclusion: Yasmin can significantly reduce vaginal bleeding after induced abortion, help endometrial repair and menstrual cycle recovery, and the contraceptive effect is good, with few complications, and it is worthy of clinical application.

       

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