Abstract: Objective: To analyze the effect of total epidural labor analgesia in the second stage of pregnancy, and analyze its influence on the satisfaction of pregnant women and the mode of delivery. Methods: 120 cases of primiparas were randomly selected from the pregnant women who were received from January 2017 to October 2017 in our hospital. The patient data were retrospectively analyzed. According to the patient’s analgesia, they were divided into three groups, 40 cases in each group. No analgesic treatment was given to the analgesic group. The control group received analgesic treatment after regular contractions, paused analgesia in the second stage of labor, and switched to normal saline. The patients in the observation group were treated with ropacaine hydrochloride after regular contractions. Combined sufentanil continued to analgesia until the end of labor. The average labor time of the three groups of pregnant women, the VAS score of perineal repair, the satisfaction of analgesia in the second stage of labor, and the mode of delivery were statistically analyzed. RESULTS: Compared with pregnant women without analgesia, the mean delivery time and perineal repair VAS scores of the control group and the observation group were significantly lower. The difference was statistically significant (P<0.05), but compared with the control group, the observation group was pregnant. The mean time of delivery was not statistically significant (P>0.05, the VAS score of perineal repair was significantly lower, and the difference was statistically significant (P<0.05). Compared with the pregnant women without analgesia, the second stage of labor of the control group and the observation group. The analgesic satisfaction score was significantly higher, the postpartum hemorrhage volume was significantly lower, and the difference was statistically significant (P<0.05). At the same time, compared with the control group, the second stage of labor analgesia satisfaction score was significantly higher in the observation group. The amount of bleeding was significantly lower, and the difference was statistically significant (P<0.05). Compared with the no analgesic group, the cesarean delivery rate was lower in the control group and the observation group, and the difference was statistically significant (P<0.05). There was no significant difference in the rate of cesarean delivery between the control group and the observation group (P>0.05). Compared with the no analgesic group, the birth weight and the different time of the control group and the observation group were significantly different. Considered significant P <0.05, but the control group and the observation of the newborn and neonatal birth weight at different times Apgar score was no significant difference P> 0.05. Conclusion: The application of full-range epidural labor analgesia in pregnant women with analgesia can achieve good analgesic effect, which can not only significantly improve the satisfaction of analgesia and perineal repair in the second stage of labor, but also reduce the rate of cesarean delivery. It is worth promoting.