Noninvasive fractional flow reserve based on X-ray coronary angiography in interventional diagnosis and treatment of coronary artery disease

Objective To explore the application value of coronary artery angiography based on automatic X-ray coronary angiography fractional flow reserve (CAFFR) compared with traditional invasive flow reserve (FFR) in the diagnosis and treatment of coronary artery disease. Methods A total of 38 patients with suspected or confirmed coronary heart disease were included in the study, with an average age of (60.47±8.2) years. CAFFR calculation method based on X-ray coronary angiography image was used to measure the FFR value, and the invasive FFR results were used as the gold standard to analyze and compare the accuracy of CAFFR in the interventional diagnosis and treatment of coronary heart disease. Pearson correlation test and Bland Altman method were used to compare the diagnostic correlation and consistency between CAFFR and FFR. Results There were 26 vessels with FFR>0.8, 25 vessels with CAFFR>0.8, 16 vessels with FFR≤0.8 and 7 vessels with CAFFR≤0.8. The diagnosis of CAFFR and FFR was consistent and correlated well (r=0.661, P<0.01). Conclusions CAFFR has good clinical value in interventional diagnosis and treatment of coronary artery disease.