Clinical analysis of 149 young and middle-aged patients with non-small cell lung cancer confirmed by surgery and pathology

Objective The clinical features of 149 young and middle-aged patients with non-small cell lung cancer (NSCLC) were evaluated to develop better understanding of diagnosis and treatment of NSCLC. Methods The clinical data of 149 young and middle-aged patients with NSCLC diagnosed by surgery and pathology who were hospitalized in the First Affiliated Hospital of Nanjing Medical University from May 2009 to August 2010 were collected. Their survival time was followed up and relevant data were analyzed. Results The mean age of 149 NSCLC patients was (55.2±8.8) years and the disease was more common in men. Adenocarcinoma accounted for the highest proportion in all pathological types, most patients were in stage Ⅰ and Ⅱ. The onset symptoms were mostly cough an1d sputum, most of the males had a history of smoking. The overall 1, 3, 5-year survival rates were 96.0%, 83.2% and 59.7%, respectively. Conclusions The majority of young and middle-aged NSCLC patients are male, and the main pathological type was adenocarcinoma. Smoking is closely related to the occurrence of lung cancer, and pathological staging is one of the factors affecting the postoperative survival time of young and middle-aged NSCLC patients.