Comparison of virtual touch tissue imaging area ratio with virtual touch tissue quantification in differential diagnosis of benign and malignant breast lesions

Objective To evaluate the area ratio of virtual touch tissue imaging (VTI) and virtual touch tissue quantification (VTQ) in differential diagnosis of benign and malignant breast lesions. Methods VTI and VTQ were performed in 68 patientswith 76 breast lesions. The area ratio of VTI and gray-scale images in breast lesions and shear wave velocity (SWV) in the lesions were obtained. Based on pathological findings, the ROC curves of VTI area ratio and SWV were constructed. The area under the curves was analyzed, while their corresponding optimal cut-off to differentially diagnose benign and malignant breast lesions was determined. Results There were no significant differences between the area under the ROC curves of VTI area ratio and SWV. The cut-off of rea ratio was no less than 1.52, with a sensitivity of 90% and a specificity of 92.6%. The cut-off of SWV was no less than 3.76 m/s, was a sensitivity of 83.3% and a specificity of 94.5%. Conclusions Both VTI area ratio and VTQ can be adopted for differential diagnosis of breast lesions without statistical differences in diagnostic efficiency.