A case-control study on the risk factors of infantile hemangioma in Xuzhou area

JIN Yingliang; ZHAO Huashuo; SUN Guixiang; CHEN Ping

doi:10.3969/j.issn.2096-3882.2022.01.009

Journal of Xuzhou Medical University > 2022 > 42(1): 45-47. > DOI: 10.3969/j.issn.2096-3882.2022.01.009

JIN Yingliang, ZHAO Huashuo, SUN Guixiang, CHEN Ping. A case-control study on the risk factors of infantile hemangioma in Xuzhou area[J]. Journal of Xuzhou Medical University, 2022, 42(1): 45-47. DOI: 10.3969/j.issn.2096-3882.2022.01.009

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A case-control study on the risk factors of infantile hemangioma in Xuzhou area

1. Department of Medical Statistics, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China;
2. Department of Dermatology, Xuzhou Children's Hospital, Xuzhou, Jiangsu 221006

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Received Date: September 28, 2020
Revised Date: October 09, 2021

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Objective To explore the risk factors of infantile hemangioma. Methods A case-control study was conducted based on Department of Dermatology, Xuzhou Children's Hospital. The cases were composed of 248 infants with superficial infantile hemangioma, while 248 infants without infantile hemangioma with the same gender and similar of age were selected as the control group. A logistic regression model was used to analyze the risk factors of infantile hemangioma, and the odds ratio of risk factors and 95% confidence interval were calculated. Results The risk factors were birth weeks (<37 weeks: P=0.124, OR=3.523, 95%CI=0.708-17.532;37-41 weeks:P=0.559,OR=1.467,95%CI=0.405-5.315), family history (P＜0.001,OR=11.816,95%CI=3.487-40.042), placenta previa (P=0.001, OR=6.034, 95%CI=2.005-18.156), the number of births (P=0.006, OR=0.592, 95%CI=0.406-0.863), and maternal hypertension (P=0.025, OR=2.749,95%CI=1.133-6.669). Conclusions Birth weeks, family history, maternal hypertension, placenta previa and birth order are risk factors for infantile hemangioma.
- hemangioma,
- case-control study,
- logistic regression,
- risk factor

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[1]	Randel A.American academy of pediatrics releases report on infantile hemangiomas[J].Am Fam Physician,2016,93(6):526-527.
[2]	Ren W,Li S,Gao L,et al.Low-dose propranolol for infantile hemangioma of the head and neck-analysis of 23 consecutive patients [J].Pediatr Int,2017,59(2)-213-217.
[3]	翁文骏,黎阳,方建培,等.4%盐酸普萘洛尔乳膏局部治疗浅表型血管瘤的疗效观察 [J].中国小儿血液与肿瘤杂志,2018,23(3)-124-126,136.
[4]	杨竞,黄惠珍,张晶,等.长脉冲1 064 nmNd:YAG激光联合噻吗洛尔滴眼液治疗婴儿血管瘤临床观察[J].中国美容医学,2019,28(5)-53-56.
[5]	李丽,马琳.婴儿血管瘤的临床表现、诊断、鉴别诊断及治疗研究进展 [J].皮肤科学通报,2018,35(5)-508-517.
[6]	李丽,马琳.儿童皮肤血管瘤分类和治疗 [J].中国实用儿科杂志,2012,27(7)-542-547.
[7]	Chinnadurai S,Sathe NA,Surawicz T.Laser treatment of infantile hemangioma:A systematic review[J].Lasers Surg Med,2016,48(3)-221-233.
[8]	Chen XD,Ma G,Chen H,et al.Maternal and perinatal risk factors for infantile hemangioma:a case-control study[J].Pediatr Dermatol,2013,30(4)-457-461.
[9]	Yang B,Li L,Zhang LX,et al.Clinical characteristics and treatment options of infantile vascular anomalies[J/OL].Medicine (Baltimore),2015,94(40)-e1717.
[10]	Ames JA,Sykes JM.Current trends in medical management of infantile hemangioma[J].Curr Opin Otolaryngol Head Neck Surg 2015,23(4)-286-291.
[11]	Greco MF,Frieden IJ,Drolet BA,et al.Infantile hemangiomas in twins:a prospective cohort study[J].Pediatr Dermatol,2016,33(2):178-183.
[12]	买买提明·马合木提,麦麦提吐尔洪·艾尼瓦尔,王建新,等.前置胎盘诊断中核磁共振成像的应用分析[J].影像研究与医学应用,2019,3(11):64-65.
[13]	Munden A,Butschek R,Tom WL,et al.Prospective study of infantile haemangiomas-incidence,clinical characteristics and association with placental anomalies[J].Br J Dermatol,2014,170(4)-907-913.
[14]	Rasul S.Clinical characteristics and risk factors for infantile hemangioma-a case control study[J].Eur J Pediatr Surg,2014,24(1):102-112.

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