Diagnostic value of transabdominal contrast-enhanced ultrasound in benign myometrial lesions of the uterus

Objective To explore the diagnostic value of transabdominal contrast-enhanced ultrasound (CEUS) in benign myometrial lesions of the uterus.Methods A total of 50 adenomyosis patients and 50 hysteromyoma patients who were subject to ultrasound (US) and CEUS in Xuzhou Central Hospital from September 2022 to August 2023 were selected. Their qualitative indexes including the enhancement mode, enhancement degree, regression mode, enhancement uniformity and enhanced boundary, as well as quantitative indexes including time to peak (TTP), peak intensity (PI) and mean transit time (MTT) were observed and compared. A receiver operating characteristic (ROC) curve was constructed, obtaining the area under the curve (AUC) and the diagnostic efficiency such as sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of US and CEUS was compared.Results Through US, 38 cases of adenomyosis and 40 cases of hysteromyoma were diagnosed, with a diagnostic consistent rate of 78%. Through CEUS, 48 cases of adenomyosis and 47 cases of hysteromyoma were diagnosed, with a diagnostic consistent rate of 95%. There were significant differences between adenomyosis and hysteromyoma in enhancement uniformity, boundary after enhancement and regression mode (P<0.05). There were no statistical differences in enhancement mode or enhancement degree (P>0.05). The TTP of adenomyosis was (39.72±5.72) s, which was shorter than (43.26±5.01) s for hysteromyoma, and the PI of adenomyosis was (70.11±4.58)%, which was lower than (75.84±4.17)% for hysteromyoma, with statistical significances (P<0.05). The MTT of adenomyosis and hysteromyoma was (85.54±6.16) s and (83.73±5.83) s respectively, without statistical difference (P>0.05). The AUC of US and CEUS was 0.78 and 0.95, respectively. CEUS showed better sensitivity, specificity, positive predictive value, negative predictive value and accuracy than CEUS in diagnosing adenomyosis, with statistical differences (P<0.05).Conclusions CEUS is useful to diagnose adenomyosis and hysteromyoma, and can effectively improve the accuracy of diagnosis results, with clinical application value.